岡村 永一

Eiichi Okamura
助教
論文一覧
2020
  • Seita Y., Morimura T., Watanabe N., Iwatani C., Tsuchiya H., Nakamura S., Suzuki T., Yanagisawa D., Tsukiyama T., Nakaya M., Okamura E., Muto M., Ema M.*, Nishimura M.*, Tooyama I.* Generation of Transgenic Cynomolgus Monkeys Overexpressing the Gene for Amyloid-β Precursor Protein. Journal of Alzheimer's Disease in press (2020)
  • Matsuzaki H., Kuramochi D., Okamura E., Hirakawa K., Ushiki A., Tanimoto K.* Recapitulation of gametic DNA methylation and its post-fertilization maintenance with reassembled DNA elements at the mouse Igf2/H19 locus. Epigenetics & chromatin 13(1) 2 - 2 (2020)
2019
  • Okamura E., Tam O.H., Posfai E., Li L., Cockburn K., Lee C.Q.E., Garner J., Rossant J.* Esrrb function is required for proper primordial germ cell development in presomite stage mouse embryos. Developmental biology 455(2) 382 - 392 (2019)
  • Tanimoto K., Matsuzaki H., Okamura E., Ushiki A., Fukamizu A., Engel J.D. Transvection-like interchromosomal interaction is not observed at the transcriptional level when tested in the Rosa26 locus in mouse. PloS one 14(2) e0203099 (2019)
2018
  • Matsuzaki H., Okamura E., Kuramochi D., Ushiki A., Hirakawa K., Fukamizu A., Tanimoto K. Synthetic DNA fragments bearing ICR cis elements become differentially methylated and recapitulate genomic imprinting in transgenic mice. Epigenetics & Chromatin Vol.11(No.1) (2018)
2015
  • Matsuzaki H., Okamura E., Takahashi T., Ushiki A., Nakamura T., Nakano T., Hata K., Fukamizu A., Tanimoto K. De novo DNA methylation through the 5'-segment of the H19 ICR maintains its imprint during early embryogenesis. Development (Cambridge, England) 142(22) 3833 - 3844 (2015)
2013
  • Sakaguchi R.#, Okamura E.#, Matsuzaki H., Fukamizu A., Tanimoto K.* Sox-Oct motifs contribute to maintenance of the unmethylated H19 ICR in YAC transgenic mice. Hum. Mol. Genet. 22(22) 4627 - 4637 (2013) (# Equal contribution)
  • Okamura E., Matsuzaki H., Fukamizu A., Tanimoto K.* The chicken HS4 insulator element does not protect the H19 ICR from differential DNA methylation in yeast artificial chromosome transgenic mouse. PLoS ONE Vol.8(No.9) e73925 - e73925 (2013)
  • Okamura E.#, Matsuzaki H.#, Sakaguchi R., Takahashi T., Fukamizu A., Tanimoto K. The H19 imprinting control region mediates preimplantation imprinted methylation of nearby sequences in yeast artificial chromosome transgenic mice. Mol. Cell. Biol. 33(4) 858 - 871 (2013) (# Equal contribution)
2012
  • Takahashi T., Matsuzaki H., Tomizawa S., Okamura E., Ichiyanagi T., Fukamizu A., Sasaki H., Tanimoto K. Sequences in the H19 ICR that are transcribed as small RNA in oocytes are dispensable for methylation imprinting in YAC transgenic mice. Gene 508(1) 26 - 34 (2012)
2010
  • Shimotsuma M., Okamura E., Matsuzaki H., Fukamizu A., Tanimoto K. DNase I Hypersensitivity and epsilon-Globin Transcriptional Enhancement Are Separable in Locus Control Region (LCR) HS1 Mutant Human beta-Globin YAC Transgenic Mice. J. Biol. Chem. 285(19) 14495 - 14503 (2010)
  • Matsuzaki H., Okamura E., Fukamizu A., Tanimoto K. CTCF binding is not the epigenetic mark that establishes post-fertilization methylation imprinting in the transgenic H19 ICR. Hum. Mol. Genet. 19(7) 1190 - 1198 (2010)
2009
  • Okamura E., Matsuzaki H., Campbell A.D., Engel J.D., Fukamizu A., Tanimoto K. All of the human beta-type globin genes compete for LCR enhancer activity in embryonic erythroid cells of yeast artificial chromosome transgenic mice. FASEB J. 23(12) 4335 - 4343 (2009)
  • Matsuzaki H., Okamura E., Shimotsuma M., Fukamizu A., Tanimoto K. A Randomly Integrated Transgenic H19 Imprinting Control Region Acquires Methylation Imprinting Independently of Its Establishment in Germ Cells. Mol. Cell. Biol. 29(17) 4595 - 4603 (2009)