業績(論文)一覧

2017

  • Azami T, Waku T, Matsumoto K, Jeon H, Muratani M, Kawashima A, Yanagisawa J, Manabe I, Nagai R, Kunath T, Nakamura T, Kurimoto K, Saitou M, Takahashi S, Ema M. Klf5 maintains the balance of primitive endoderm to epiblast specification during mouse embryonic development by suppression of Fgf4. Development. 2017 Sep 4. pii: dev.150755. doi: 10.1242/dev.150755.
  • Zhong W, Gao X, Wang S, Han K, Ema M, Adams S, Adams RH, Rosenblatt MI, Chang JH, Azar DT. Prox1-GFP/Flt1-DsRed transgenic mice: an animal model for simultaneous live imaging of angiogenesis and lymphangiogenesis. Angiogenesis. 2017 Aug 9. doi: 10.1007/s10456-017-9572-7.
  • Matsushita J, Inagaki S, Nishie T, Sakasai T, Tanaka J, Watanabe C, Mizutani KI, Miwa Y, Matsumoto K, Takara K, Naito H, Kidoya H, Takakura N, Nagai T, Takahashi S, Ema M. Fluorescence and Bioluminescence Imaging of Angiogenesis in Flk1-Nano-lantern Transgenic Mice. Sci Rep. 7:46597. (2017)
  • Yamazaki T, Nalbandian A, Uchida Y, Li W, Arnold TD, Kubota Y, Yamamoto S, Ema M, MukouyamaYS. Tissue Myeloid Progenitors Differentiate into Pericytes through TGF-β Signaling in Developing Skin Vasculature. Cell Rep. 18:2991-3004. (2017)
  • Ogura S, Kurata K, Hattori Y, Takase H, Ishiguro-Oonuma T, Hwang Y, Ahn S, Park I, Ikeda W, Kusuhara S, Fukushima Y, Nara H, Sakai H, Fujiwara T, Matsushita J, Ema M, Hirashima M, Minami T, Shibuya M, Takakura N, Kim P, Miyata T, Ogura Y, Uemura A. Sustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdown. JCI Insight. 2(3):e90905. (2017)

2016

  • Kawaguchi T., Cho D., Hayashi M., Tsukiyama T., Kimura K., Matsuyama S., Minami N., Yamada M. and Imai H. Derivation of Induced Trophoblast Cell Lines in Cattle by Doxycycline-Inducible piggyBac Vectors. PLoS One. 11(12):e0167550. (2016)
  • Sasaki K, Nakamura T, Okamoto I, Yabuta Y, Iwatani C, Tsuchiya H, Seita Y, Nakamura S, Shiraki N, Takakuwa T, Yamamoto T, Saitou M. The Germ Cell Fate of Cynomolgus Monkeys Is Specified in the Nascent Amnion. Dev Cell. 39(2):169-185 (2016)
  • Hara H, Ono F, Nakamura S, Matsumoto SE, Jin H, Hattori N, Tabira T. An Oral Aβ Vaccine Using a Recombinant Adeno-Associated Virus Vector in Aged Monkeys: Reduction in Plaque Amyloid and Increase in Aβ Oligomers. J. Alzheimers. Dis. 54(3):1047-1059. (2016)
  • Nakamura T, Okamoto I, Sasaki K, Yabuta Y, Iwatani C, Tsuchiya H, Seita Y, Nakamura S, Yamamoto T & Saitou M. A developmental coordinate of pluripotency among mice, monkeys and humans. Nature. 537(7618):57-62 (2016)
  • Khoa le TP, Azami T, Tsukiyama T, Matsushita J, Tsukiyama-Fujii S, Takahashi S, Ema M. Visualization of the Epiblast and Visceral Endodermal Cells Using Fgf5-P2A-Venus BAC Transgenic Mice and Epiblast Stem Cells. PLoS One. 11(7):e0159246. (2016)
  • Yoshikawa Y, Yamada T, Tai-Nagara I, Okabe K, Kitagawa Y, Ema M, Kubota Y. Developmental regression of hyaloid vasculature is triggered by neurons. J Exp Med. 2016 Jun 20. pii: jem.20151966. [Epub ahead of print]
  • Adachi M, Kisu I, Nagai T, Emoto K, Banno K, Umene K, Nogami Y, Tsuchiya H, Itagaki I, Kawamoto I, Nakagawa T, Ogasawara K, Aoki D. Evaluation of allowable time and histopathological changes in warm ischemia of the uterus in cynomolgus monkey as a model for uterus transplantation. Acta Obstet Gynecol Scand. 2016 Jun 22. doi: 10.1111/aogs.12943. [Epub ahead of print]
  • Koyama S, Fukuda K, Watanabe S, Kohara S, Tsuchiya H, Fukuzaki K, Nagano M, Uno Y, Hosoi Y. Development of a new device for artificial insemination in cynomolgus macaques. J Reprod Dev. 2016 Jun 17. [Epub ahead of print]
  • Seita Y, Tsukiyama T, Iwatani C, Tsuchiya H, Matsushita J, Azami T, Okahara J, Nakamura S, Hayashi Y, Hitoshi S, Itoh Y, Imamura T, Nishimura M, Tooyama I, Miyoshi H, Saitou M, Ogasawara K, Sasaki E, Ema M. Generation of transgenic cynomolgus monkeys that express green fluorescent protein throughout the whole body. Sci Rep. 6:24868. (2016)
  • Jeon H, Waku T, Azami T, Khoa le TP, Yanagisawa J, Takahashi S, Ema M. Comprehensive Identification of Krüppel-Like Factor Family Members Contributing to the Self-Renewal of Mouse Embryonic Stem Cells and Cellular Reprogramming. PLoS One. 11(3):e0150715. (2016)
  • Okumura N, Sakamoto Y, Fujii K, Kitano J, Nakano S, Tsujimoto Y, Nakamura S, Ueno M, Hagiya M, Hamuro J, Matsuyama A, Suzuki S, Shiina T, Kinoshita S, Koizumi N. Rho kinase inhibitor enables cell-based therapy for corneal endothelial dysfunction. Sci Rep. 6:26113 (2016)

2015

  • Matsuo K, Kuroda Y, Nango N, Shimoda K, Kubota Y, Ema M, Bakiri L, Wagner EF, Takeda Y, Yashiro W, Momose A. Osteogenic capillaries orchestrate growth plate-independent ossification of the malleus. Development 142(22):3912-20. (2015)
  • Kawaguchi T., Tsukiyama T., Kimura K., Matsuyama S., Minami N., Yamada M. and Imai H. Generation of naive bovine induced pluripotent stem cells using piggyBac transposition of doxycycline-inducible transcription factors. PLoS ONE 10:e0135403. (2015)
  • Hongu T., Funakoshi Y., Fukuhara S., Suzuki T., Sakimoto S., Takakura N., Ema M., Takahashi S., Itoh S., Kato M., Hasegawa H, Mochizuki N., Kanaho Y. Arf6 regulates tumor angiogenesis and growth through HGF-induced endothelial 1 integrin recycling. Nat Commun, 6:7925. (2015)
  • Shiina T, Yamada Y, Aarnink A, Suzuki S, Masuya A, Ito S, Ido D, Yamanaka H, Iwatani C, Tsuchiya H, Ishigaki H, Itoh Y, Ogasawara K, Kulski JK, Blancher A. Discovery of novel MHC-class I alleles and haplotypes in Filipino cynomolgus macaques (Macaca fascicularis) by pyrosequencing and Sanger sequencing: Mafa-class I polymorphism.Immunogenetics. 67(10):563-78. (2015)
  • Sasaki K, Yokobayashi S, Nakamura T, Okamoto I, Yabuta Y, Kurimoto K, Ohta H, Moritoki Y, Iwatani C, Tsuchiya H, Nakamura S, Sekiguchi K, Sakuma T, Yamamoto T, Mori T, Woltjen K, Nakagawa M, Yamamoto T, Takahashi K, Yamanaka S, Saitou M. Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells. Cell Stem Cell. 17(2):178-94. (2015)
  • Itoh Y, Shichinohe S, Nakayama M, Igarashi M, Ishii A, Ishigaki H, Ishida H, Kitagawa N, Sasamura T, Shiohara M, Doi M, Tsuchiya H, Nakamura S, Okamatsu M, Sakoda Y, Kida H, Ogasawara K. Emergence of H7N9 Influenza A Virus Resistant to Neuraminidase Inhibitors in Nonhuman Primates. Antimicrob Agents Chemother. 59(8):4962-73. (2015)
  • Iizuka S, Sakurai F, Shimizu K, Ohashi K, Nakamura S, Tachibana M, Mizuguchi H. Evaluation of transduction properties of an adenovirus vector in neonatal mice. Biomed Res Int. 2015;2015:685374
  • Katano M, Ema M, Nakachi Y, Mizuno Y, Hirasaki M, Suzuki A, Ueda A, Nishimoto M, Takahashi S, Okazaki Y, Okuda A. Forced expression of Nanog or Esrrb preserves the ESC status in the absence of nucleostemin expression. Stem Cells. 33:1089-1101. (2015)
  • Suzuki S., Tsukiyama T., Kaneko T., Imai H. and Minami N. A hyperactive piggyBac transposon system is an easy-to-implement method for introducing foreign genes into mouse preimplantation embryos. The Journal of Reproduction and Development, 61:241-244. (2015)
  • Hishida T, Nakachi Y, Mizuno Y, Katano M, Okazaki Y, Ema M, Takahashi S, Hirasaki M, Suzuki A, Ueda A, Nishimoto M, Hishida-Nozaki Y, Vazquez-Ferrer E, Sancho-Martinez I, Izpisua Belmonte JC, Okuda A. Functional compensation between Myc and PI3K signaling supports self-renewal of embryonic stem cells. Stem Cells. 33:713-725. (2015)
  • Masuda T, Otsu K, Kumakami-Sakano M, Fujiwara N, Ema M, Hitomi J, Sugiyama Y, and Harada H. Combined administration of BMP-2 and HGF facilitate bone regeneration through angiogenic mechanisms. J., Hard Tissue Biol. 24(1): 7-16. (2015)

2014

  • Okabe K, Kobayashi S, Yamada T, Kurihara T, Tai-Nagara T, Miyamoto T, Mukouyama Y, Sato TN, Suda T, Ema M, Kubota Y, Neurons limit angiogenesis by titrating VEGF in retina, Cell 159: 584–596 (2014)
  • Kowata S, Isogai S, Murai K, Ito S, Tohyama K, Ema M, Hitomi J, Ishida Y. Platelet demand modulates the type of intravascular protrusion of megakaryocytes in bone marrow. Thromb Haemost. 112:743-756. (2014)
  • Matsumoto K, Ema M. Roles of VEGF-A signalling in development, regeneration, and tumours. J Biochem. 156:1-10. (2014)
  • Hasegawa Y, Daitoku Y, Mizuno S, Tanimoto Y, Mizuno-Iijima S, Matsuo M, Kajiwara N, Ema M, Oishi H, Miwa Y, Mekada K, Yoshiki A, Takahashi S, Sugiyama F, Yagami K. Generation and characterization of Ins1-cre-driver C57BL/6N for exclusive pancreatic beta cell-specific Cre-loxP recombination. Exp Anim. 63:183-191. (2014)
  • Moi ML, Takasaki T, Omatsu T, Nakamura S, Katakai Y, Ami Y, Suzaki Y, Saijo M, Akari H, Kurane I. Demonstration of marmosets (Callithrix jacchus) as a non-human primate model for secondary dengue virus infection: high levels of viraemia and serotype cross-reactive antibody responses consistent with secondary infection of humans. J Gen Virol. 95(3): 591-600. (2014)
  • Shimizu K, Sakurai F, Tomita K, Nagamoto Y, Nakamura S, Katayama K, Tachibana M, Kawabata K, Mizuguchi H. Suppression of leaky expression of adenovirus genes by insertion of microRNA-targeted sequences in the replication-incompetent adenovirus vector genome. Mol Ther Methods Clin Dev. 1:14035. (2014)
  • Itoh Y, Yoshida R, Shichinohe S, Higuchi M, Ishigaki H, Nakayama M, Pham VL, Ishida H, Kitano M, Arikata M, Kitagawa N, Mitsuishi Y, Ogasawara K, Tsuchiya H, Hiono T, Okamatsu M, Sakoda Y, Kida H, Ito M, Quynh Mai L, Kawaoka Y, Miyamoto H, Ishijima M, Igarashi M, Suzuki Y, Takada A. Protective efficacy of passive immunization with monoclonal antibodies in animal models of H5N1 highly pathogenic avian influenza virus infection. PLoS Pathog. 10(6):e1004192. (2014)
  • Kitano M, Itoh Y, Ishigaki H, Nakayama M, Ishida H, Pham VL, Arikata M, Shichinohe S, Tsuchiya H, Kitagawa N, Kobayashi M, Yoshida R, Sato A, Le QM, Kawaoka Y, Ogasawara K. Efficacy of repeated intravenous administration of peramivir against highly pathogenic avian influenza A (H5N1) virus in cynomolgus macaques. Antimicrob Agents Chemother. 58(8):4795-803. (2014)
  • Kisu I, Kato Y, Tsuchiya H, Kawamoto I, Nakagawa T, Ogasawara K, Hayakawa T, Yamayoshi Y, Iketan O, Mihara M, Banno K, Sato S, Shiina T, Aoki D. Pharmacokinetic Properties of Cyclosporine A after Subcutaneous Injection in Cynomolgus Monkey. Study of International Journal of Pharmacology (2014)

2013

  • Hasegawa Y, Daitoku Y, Sekiguchi K, Tanimoto Y, Iijima S, Mizuno S, Kajiwara N, Ema M, Miwa Y, Mekada K, Yoshiki A, Takahashi S, Sugiyama F, Yagami K. Novel ROSA26 Cre-reporter knock-in C57BL/6N mice exhibiting green emission before and red emission after Cre-mediated recombination. Exp Anim 62:295-304. (2013)
  • Kudo T, Sato T, Hagiwara K, Kozuma Y, Yamaguchi T, Ikehara Y, Hamada M, Matsumoto K, Ema M, Murata S, Ohkohchi N, Narimatsu H, Takahashi S. C1galt1-deficient mice exhibit thrombocytopenia due to abnormal terminal differentiation of megakaryocytes. Blood. 122:1649-1657. (2013)
  • Nishimoto M, Katano M, Yamagishi T, Hishida T, Kamon M, Suzuki A, Hirasaki M, Nabeshima Y, Nabeshima Y, Katsura Y, Satta Y, Deakin JE, Graves JA, Kuroki Y, Ono R, Ishino F, Ema M, Takahashi S, Kato H, Okuda A. In vivo function and evolution of the eutherian-specific pluripotency marker UTF1. PLoS One. 8:e68119. (2013)
  • Yoshida T, Omatsu T, Saito A, Katakai Y, Iwasaki Y, Kurosawa T, Hamano M, Higashino A, Nakamura S, Takasaki T, Yasutomi Y, Kurane I, Akari H. Dynamics of cellular immune responses in the acute phase of dengue virus infection. Arch Virol. 158:1209-1220. (2013)
  • Lebrun C., Avci HX., Wehrlé R., Doulazmi M., Jaudon F., Morel MP., Rivals I.,Ema M., Schmidt S., Sotelo C., Vodjdani G., Dusart I. Klf9 is necessary and sufficient for Purkinje cell survival in organotypic culture. Mol Cell Neurosci. 54:9-21. (2013)
  • Nakayama M, Shichinohe S, Itoh Y, Ishigaki H, Kitano M, Arikata M, Pham VL, Ishida H, Kitagawa N, Okamatsu M, Sakoda Y, Ichikawa T, Tsuchiya H, Nakamura S, Le QM, Ito M, Kawaoka Y, Kida H, Ogasawara K. Protection against H5N1 highly pathogenic avian and pandemic (H1N1) 2009 influenza virus infection in cynomolgus monkeys by an inactivated H5N1 whole particle vaccine. PLoS One. 8:e82740. (2013)
  • Pham VL, Nakayama M, Itoh Y, Ishigaki H, Kitano M, Arikata M, Ishida H, Kitagawa N, Shichinohe S, Okamatsu M, Sakoda Y, Tsuchiya H, Nakamura S, Kida H, Ogasawara K. Pathogenicity of pandemic H1N1 influenza A virus in immunocompromised cynomolgus macaques. PLoS One. 8:e75910 (2013)
  • Moi ML, Omatsu T, Hirayama T, Nakamura S, Katakai Y, Yoshida T, Saito A, Tajima S, Ito M, Takasaki T, Akari H, Kurane I. Presence of viral genome in urine and development of hematuria and pathological changes in kidneys in common marmoset (Callithrix jacchus) after inoculation with dengue virus. Pathogen. 2:357-363. (2013)
  • Okumura N, Koizumi N, Kay EP, Ueno M, Sakamoto Y, Nakamura S, Hamuro J, Kinoshita S. The ROCK inhibitor eye drop accelerates corneal endothelium wound healing. Invest Ophthalmol Vis Sci. 54:2493-2502. (2013)
  • Katsumata T, Oishi H, Sekiguchi Y, Nagasaki H, Daassi D, Tai PH, Ema M, Kudo T, Takahashi S. Bioluminescence imaging of β cells and intrahepatic insulin gene activity under normal and pathological conditions. PLoS One. 8:e60411. (2013)
  • Fujishiro SH., Nakano K., Mizukami Y., Azami T., Arai Y., Matsunari H., Ishino R., Nishimura T., Watanabe M., Abe T., Furukawa Y., Umeyama K., Yamanaka S., Ema M., Nagashima H., Hanazono Y. Generation of Naive-like Porcine Induced Pluripotent Stem Cells Capable of Contributing to Embryonic and Fetal Development. Stem Cells Dev. 22:473-482. (2013)

2012

  • Oishi H, Itoh S, Matsumoto K, Ishitobi H, Suzuki R, Ema M, Kojima T, Uchida K, Kato M, Miyata T, Takahashi S, Delayed cutaneous wound healing in Fam129b/Minerva-deficient mice. J. Biochem. 152:549-555. (2012)
  • Omatsu T, Moi ML, Takasaki T, Nakamura S, Katakai Y, Tajima S, Ito M, Yoshida T, Saito A, Akari H, Kurane I. Changes in hematological and serum biochemical parameters in common marmosets (Callithrix jacchus) after inoculation with dengue virus. J Med Primatol. 41:289-296. (2012)
  • Sugimoto C, Nakamura S, Hagen SI, Tsunetsugu-Yokota Y, Villinger F, Ansari AA, Suzuki Y, Yamamoto N, Nagai Y, Picker LJ, Mori K. Glycosylation of simian immunodeficiency virus influences immune-tissue targeting during primary infection, leading to immunodeficiency or viral control. J Virol. 86:9323-9336. (2012)
  • Nishimura M, Nakamura S, Kimura N, Liu L, Suzuki T, Tooyama I. Age-related modulation of γ-secretase activity in non-human primate brains. J Neurochem. 123:21-28. (2012)
  • Takase H., Matsumoto K., Yamadera R., Kubota Y., Otsu A., Suzuki R., Ishitobi H., Mochizuki H., Kojima T., Takano S., Uchida K., Takahashi S., Ema M. Genome-wide identification of endothelial cell-enriched genes in the mouse embryo. Blood 120:914-923. (2012)
  • Matsumoto K., Azami T., Otsu A., Takase H., Ishitobi H., Tanaka J., Miwa Y., Takahashi S., Ema M. Study of normal and pathological blood vessel morphogenesis in Flt1-tdsRed BAC Tg mice. Genesis. 50:561-571. (2012)
  • Arikata M, Itoh Y, Okamatsu M, Maeda T, Shiina T, Tanaka K, Suzuki S, Nakayama M, Sakoda Y, Ishigaki H, Takada A, Ishida H, Soda K, Pham VL, Tsuchiya H, Nakamura S, Torii R, Shimizu T, Inoko H, Ohkubo I, Kida H, Ogasawara K. Memory immune responses against pandemic (H1N1) 2009 influenza virus induced by a whole particle vaccine in cynomolgus monkeys carrying Mafa-A1*052:02. PLoS One. 7:e37220. (2012)
  • Sano K., Katsuta O., Shirae S., Kubota Y., Ema M., Suda T., Nakamura M., Hirashima M. Flt1 and Flk1 mediate regulation of intraocular pressure and their double heterozygosity causes the buphthalmia in mice. Biochem Biophys Res Commun. 420:422-427 (2012)
  • Avci HX., Lebrun C., Wehrlé R., Doulazmi M., Chatonnet F., Morel MP.,Ema M., Vodjdani G., Sotelo C., Flamant F., Dusart I. Thyroid hormone triggers the developmental loss of axonal regenerative capacity via thyroid hormone receptor α1 and kruppel-like factor 9 in Purkinje cells. Proc Natl Acad Sci U S A. 109:14206-14211 (2012)
  • Okahara-Narita J, Umeda R, Nakamura S, Mori T, Noce T, Torii R. Induction of pluripotent stem cells from fetal and adult cynomolgus monkey fibroblasts using four human transcription factors. Primates. 53:205-213. (2012)
  • Nakamura S, Tsuchiya H, Okahara N, Nakagawa T, Ohara N, Yamamoto H, Li T, Takeda N, Ogasawara K, Torii R. Epidemiology of Hepatitis E Virus in Indoor-Captive Cynomolgus Monkey Colony. J Vet Med Sci. 57;279-283. (2012)
  • Ueda M, Ageyama N, Nakamura S, Nakamura M, Chambers J, Misumi Y, Mizuguchi M, Shinriki S, Kawahara S, Tasaki M, Jono H, Obayashi K, Sasaki E, Une Y, Ando Y. Aged vervet monkeys developing transthyretin amyloidosis with the human disease-causing Ile122 allele: A valid pathological model of the human disease. Lab Invest. 92:474-484. (2012)
  • Yoshida T, Omatsu T, Saito A, Katakai Y, Iwasaki Y, Iijima S, Kurosawa T, Hamano M, Nakamura S, Takasaki T, Yasutomi Y, Kurane I, Akari H. CD16 positive natural killer cells play a limited role against primary dengue virus infection in tamarins. Arch Virol. 157:363-368. (2012)
  • Morichika J, Iwatani C, Tsuchiya H, Nakamura S, Sankai T, Torii R. Triplet pregnancy in a cynomolgus monkey (Macaca fascicularis) after double embryo transfer. Comp Med. 62:69-72. (2012)
  • Toyoshima Y, Sekiguchi S, Negishi T, Nakamura S, Ihara T, Ishii Y, Kyuwa S, Yoshikawa Y, Takahashi K. Differentiation of neural cells in fetal cerebral cortex of cynomolgus monkeys (Macaca fascicularis). Comp Med. 62:53-60. (2012)

2011

  • Kuroda T, Murayama A, Katagiri N, Ohta Y, Fujita E, Masumoto H, Ema M, Takahashi S, Kimura K, Yanagisawa J. RNA content in the nucleolus alters p53 acetylation via MYBBP1A. EMBO J. 30, 1054-1066 (2011)
  • Nakamura S, Ueda M, Ageyama N, Ando Y, Torii R. : Transthyretin amyloidosis in aged vervet monkeys, as a candidate for the spontaneous animal model of senile systemic amyloidosis. (Sarantseva S. ed.) INTECH, (Rijeka, Croatia), 181-190, (2011)
  • Sato T., Kudo T., Ikehara Y., Ogawa H., Hirano T., Kiyohara K., Hagiwara K., Togayachi A., Ema M., Takahashi S., Kimata K., Watanabe H., Narimatsu H.: Chondroitin sulfate N-acetylgalactosaminyltransferase 1 is necessary for normal endochondral ossification and aggrecan metabolism. J Biol Chem. 286:5803-5812. (2011)
  • Kumadaki S., Karasawa T., Matsuzaka T., Ema M., Nakagawa Y., Nakakuki M., Saito R., Yahagi N., Iwasaki H., Sone H., Takekoshi K., Yatoh S., Kobayashi K., Takahashi A., Suzuki H., Takahashi S., Yamada N., Shimano H. Inhibition of Ubiquitin ligase F-box and WD repeat domain-containing 7{alpha} (Fbw7{alpha}) causes hepatosteatosis through the Kruppel-like factor 5 (KLF5)/PPAR{gamma}2 pathway, but not SREBP-1c in mice. J Biol Chem. 286, 40835-40846 (2011)
  • Hishida T, Nozaki Y, Nakachi Y, Mizuno Y, Okazaki Y, Ema M, Takahashi S, Nishimoto M, Okuda A. Indefinite Self-Renewal of ESCs through Myc/Max Transcriptional Complex-Independent Mechanisms. Cell Stem Cell 9, 37-49 (2011)
  • Kajiro M, Tsuchiya M, Kawabe Y, Furumai R, Iwasaki N, Hayashi Y, Katano M, Nakajima Y, Goto N, Watanabe T, Murayama A, Oishi H, Ema M, Takahashi S, Kishimoto H, Yanagisawa J. The E3 ubiquitin ligase activity of Trip12 is essential for mouse embryogenesis. PLoS One. 6(10):e25871 (2011)
  • Omatsu T, Moi ML, Hirayama T, Takasaki T, Nakamura S, Tajima S, Ito M, Yoshida T, Saito A, Katakai Y, Akari H, Kurane I. Common marmoset (Callithrix jacchus) as a primate model of dengue virus infection: development of high levels of viraemia and demonstration of protective immunity. J Gen Virol. 92:2272-2280. (2011)
  • Kubota Y, Takubo K, Hirashima M, Nagoshi N, Kishi K, Okuno Y, Nakamura-Ishizu A, Sano K. Murakami M, Ema M, Omatsu Y, Takahashi S, Nagasawa T, Shibuya M, Okano H, Suda T. Isolation and function of tissue resident vascular precursors marked by myelin protein zero. J. Exp. Med. 208, 949-960 (2011)
  • Ishitobi H, Wakamatsu A, Liu F, Azami T, Hamada M, Matsumoto K, Kataoka H, Kobayashi M, Choi K, Nishikawa S, -I, Takahashi S, Ema M. Molecular basis for Flk1 expression in hemato-cardiovascular progenitors in the mouse. Development 138, 5357-5368 (2011)

2010

  • Verma M., Asakura Y., Hirai H., Watanabe S., Tastad C., Fong GH., Ema M., Call JA,, Lowe DA,, Asakura A.: Flt-1 haploinsufficiency ameliorates muscular dystrophy phenotype by developmentally increased vasculature in mdx mice. Hum Mol Genet. 19: 4145-4159. (2010)
  • Ishitobi H., Matsumoto K., Azami T., Itoh F., Itoh S., Takahashi S., Ema M.: Flk1-GFP BAC Tg mice: an animal model for the study of blood vessel development. Exp. Animals, 59: 615-622. (2010)
  • Ushitora M, Sakurai F, Yamaguchi T, Nakamura S, Kondoh M, Yagi K, Kawabata K, Mizuguchi H. Prevention of hepatic ischemia-reperfusion injury by pre-administration of catalase-expressing adenovirus vectors. J Control Release. 142:431-437. (2010)
  • Shimozawa N, Nakamura S, Takahashi I, Hatori M, Sankai T. Characterization of a novel embryonic stem cell line from an intracytoplasmic sperm injection-derived blastocyst in the African green monkey. Reproduction. 139:565-573. (2010)
  • Kojima T., Hirota Y., Ema M., Takahashi S., Miyoshi I., Okano H., Sawamoto K.: Subventricular zone-derived neural progenitor cells migrate along a blood vessel scaffold toward the post-stroke striatum. Stem Cells, 28:545-554. (2010)